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This internal cream is only intended for vaginal thrush, and should only be applied using the applicator that comes with the medicine. It should be applied once a day, usually at night just before you go to bed. You should use it for 7 days, even if you’re on your period. Whilst using gyno-Daktarin, it’s best to avoid sex, as there’s a small chance that the infection can be passed to your partner. There’s also a likelihood that the cream can damage a condom, so you might not be protected against STIs and pregnancy.